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Clinical Trials
Please be aware that this page may not always be current. Updated information regarding clinical trials can be found searching for "desmoid tumor", “aggressive fibromatosis”, or even “fibromatosis.” at the National Cancer Institute’s website www.clinicaltrials.gov or Medpedia Project page at www.medpedia.com/clinical-trials
The following are ongoing or recently closed trials including desmoids:
Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP) (CHIP) |
This study is currently recruiting participants.
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Last Updated: November 2011 |
| Sponsored by: |
Pfizer |
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| Information provided by: |
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| Clinical Trials.gov Identifier: |
NCT00585312 |
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For detailed information click here: |
http://clinicaltrials.gov/ct2/show/NCT00585312 |
To compare the time from randomization to treatment failure over a 5 year period in subjects treated with celecoxib vs placebo
The trial is currently enrolling subjects (10 to 17 years of age) with FAP and an intact colon into a study assessing the effectiveness and safety of Celebrex versus placebo in the prevention of colorectal polyps. If interested call Carol Burke, M. D. at 216/444-6864 or Hennie Hasson, R.N. at 216/444-6975.
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Endoxifen in Adults With Hormone Receptor-Positive Solid Tumors |
This study is currently recruiting participants.
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Last Updated: March 2011 |
| Sponsored by: |
National Cancer Institute (NCI) |
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| Information provided by: |
National Institutes of Health Clinical Center (CC) |
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| Clinical Trials.gov Identifier: |
NCT01273168 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ct2/show
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To test the safety and effectiveness of daily endoxifen in individuals with hormone receptor-positive solid tumors that have not responded to standard treatment.
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| Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors |
This study isongoing.
Last Updated: June 2011 |
| Sponsored by: |
University of Pennsylvania |
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| Information provided by: |
University of Pennsylvania |
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| Clinical Trials.gov Identifier: |
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For detailed information click here: |
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The Role of Hydroxyurea as First Line Treatment for Primary Desmoid Tumors in Adults: You may be eligible to participate in this study if you have been diagnosed with a desmoid tumor and you have not been treated with chemotherapy. The study is being done to research how effective and safe the medication, hydroxyurea is in the treatment of desmoid tumors.
The Role of Hydroxyurea in the Treatment of Recurrent or Refractory Desmoid Tumors in Adults: You may be eligible to participate in this study if you have been diagnosed with a desmoid tumor and you have had chemotherapy in which the tumor did not respond. The study is being done to research how effective and safe the medication, hydroxyurea is in the treatment of desmoid tumors.
If you are eligible, you will take hydroxyurea, which is a tablet, by mouth daily. You will have to have an office visit every 4 weeks. You will have a CT scan or MRI every 12 weeks while on this study to help evaluate if the drug is effective. Patients will remain on the drug for up to one year as long as there is a response or stabiliy in tumor size and/or pain. If you are interested in more information, please contact Deb Riordan at 215-829-6712. |
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| Radiation Therapy in Treating Patients with Aggressive Fibromatoses (Phase II) |
This study is ongoing, but not recruiting participants.
Last Updated: February 6, 2009 |
| Sponsored by: |
European Organization for Research and Treatment of Cancer |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00030680 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ct2/show
/NCT00030680 |
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| Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma |
This study is currently recruiting participants.
Verified by National Cancer Institute (NCI), Last Updated: December 14, 2010 |
| Sponsored by: |
Children's Oncology Group National Cancer Institute (NCI)
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00919269 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ ct2/show/NCT00919269 |
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| Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis (Phase I/II) |
This study is currently recruiting participants.
Verified by National Cancer Institute (NCI) Last Updated: July 15, 2010 |
| Sponsored by: |
National Cancer Institute (NCI)
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00287846 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ct2/show/NCT00287846 |
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| Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain |
This study has been completed.
Last Updated: November 4, 2010 |
| Sponsored by: |
Insys Therapeutics Inc |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00538850 |
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For detailed information click here: |
http://clinicaltrials.gov/show/NCT00538850 |
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| MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma |
This study has been completed.
Last Updated: May 25, 2010 |
| Sponsored by: |
National Cancer Institute (NCI) |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00020579 |
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For detailed information click here: |
http://clinicaltrials.gov/show/NCT00020579 |
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| Vinblastine and Methotrexate in Treating Children With Desmoid Tumors (Phase II) |
This study has been completed.
Last Updated: November 2, 2010 |
| Sponsored by: |
National Cancer Institute (NCI)
Children's Cancer Group
Pediatric Oncology Group |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00003019 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ct2/
show/NCT00003019 |
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| Toremifene in Treating Patients With Desmoid Tumors (Phase II) |
This study has been completed
Last Updated: September 1, 2010 |
| Sponsored by: |
Lutheran General Hospital |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00002595 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ ct2/show/NCT00002595 |
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| Sulindac and Tamoxifen in Treating Patients with Desmoid Tumors (Phase II) |
This study has been completed.
Last Updated: December 14, 2010 |
| Sponsored by: |
Children's Oncology Group
National Cancer Institute (NCI) |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00068419 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ct2/show/
NCT00068419 |
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| Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas (Phase II) |
This study has been completed.
Last Updated:October 16, 2009 |
| Sponsored by: |
Memorial Sloan-Kettering Cancer Center National Cancer Institute (NCI) |
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| Information provided by: |
National Cancer Institute (NCI) |
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| Clinical Trials.gov Identifier: |
NCT00474994 |
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For detailed information click here: |
http://www.clinicaltrials.gov/ct2/show/
NCT00474994 |
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