References for Stephen X. Skapek, MD

2009

p18Ink4c and p53 act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor. Cancer Research, 69(2), 440-448.

Saab, R., Rodriguez-Galindo, C., Matmati, K., Rehg, J. E., Baumer, S. H., Khoury, J. D., et al.

2008

Pediatric nonrhabdomyosarcoma soft tissue sarcomas. Oncologist, 13(6), 668-678.

Spunt, S. L., Skapek, S. X., & Coffin, C. M.

2008

Prolactinoma as the first manifestation of gardner's syndrome. Pediatric Blood and Cancer, 50(2), 409-412.

Goodin, G. S., McCarville, M. B., Thibodeau, S. N., Skapek, S. X., Khoury, J. D., & Spunt, S. L.

2008

Hematometrocolpos in an adolescent female treated for pelvic ewing sarcoma. Pediatric Blood and Cancer, 50(1), 157-160.

Gaillard, P., Krasin, M. J., Laningham, F. H., Hoffer, F. A., Davidoff, A. M., Spunt, S. L., et al.

2007

MRI and biologic behavior of desmoid tumors in children. American Journal of Roentgenology, 189(3), 633-640.

McCarville, M. B., Hotter, F. A., Adelman, C. S., Khoury, J. D., Li, C., & Skapek, S. X.

2007

Continuous delivery of IFN-β promotes sustained maturation of intratumoral vasculature. Molecular Cancer Research, 5(6), 531-542.

Dickson, P. V., Hamner, J. B., Streck, C. J., Ng, C. Y. C., McCarville, M. B., Calabrese, C., et al.

2007

Distinguishing undifferentiated embryonal sarcoma of the liver from biliary tract rhabdomyosarcoma: A children's oncology group study. Pediatric and Developmental Pathology, 10(2), 89-97.

Nicol, K., Savell Jr., V., Moore, J., Teot, L., Spunt, S. L., Qualman, S., et al.

2007

Vinblastine and methotrexate for desmoid fibromatosis in children: Results of a pediatric oncology group phase II trial. Journal of Clinical Oncology, 25(5), 501-506.

Skapek, S. X., Ferguson, W. S., Granowetter, L., Devidas, M., Perez-Atayde, A. R., Dehner, L. P., et al.

2007

Persistent hyperplastic primary vitreous due to somatic mosaic deletion of the arf tumor suppressor. Investigative Ophthalmology and Visual Science, 48(2), 491-499.

Thornton, J. D., Swanson, D. J., Mary, M. N., Pei, D., Martin, A. C., Pounds, S., et al.

2006

Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma. Modern Pathology, 19(9), 1213-1220.

Ganti, R., Skapek, S. X., Zhang, J., Fuller, C. E., Wu, J., Billups, C. A., et al.

2006

Regulation of cell lineage specification by the retinoblastoma tumor suppressor. Oncogene, 25(38), 5268-5276.

Skapek, S. X., Pan, Y. -., & Lee, E. Y. -. P.

2006

Pharmacologic inhibition of cyclin-dependent kinase 4/6 activity arrests proliferation in myoblasts and rhabdomyosarcoma-derived cells. Molecular Cancer Therapeutics, 5(5), 1299-1308.

Saab, R., Bills, J. L., Miceli, A. P., Anderson, C. M., Khoury, J. D., Fry, D. W., et al.

2005

The arf tumor suppressor regulates platelet-derived growth factor receptor β signaling: A new view through the eyes of arf-/- mice. Cell Cycle, 4(10), 1316-1319.

Thornton, J. D., Silva, R. L. A., Martin, A. C., & Skapek, S. X.

2005

Arf-dependent regulation of pdgf signaling in perivascular cells in the developing mouse eye. EMBO Journal, 24(15), 2803-2814.

Silva, R. L. A., Thornton, J. D., Martin, A. C., Rehg, J. E., Bertwistle, D., Zindy, F., et al.

2004

Pathogenesis of persistent hyperplastic primary vitreous in mice lacking the arf tumor suppressor gene. Investigative Ophthalmology and Visual Science, 45(10), 3387-3396.

Martin, A. C., Thornton, J. D., Liu, J., Wang, X., Zuo, J., Jablonski, M. M., et al.

2003

Arf tumor suppressor promoter monitors latent oncogenic signals in vivo. Proceedings of the National Academy of Sciences of the United States of America, 100(26), 15930-15935.

Zindy, F., Williams, R. T., Baudino, T. A., Rehg, J. E., Skapek, S. X., Cleveland, J. L., et al.

2002

Synovial sarcoma in pediatric patients. American Journal of Roentgenology, 179(3), 797-801.

McCarville, M. B., Spunt, S. L., Skapek, S. X., & Pappo, A. S.

2002

The arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development. Proceedings of the National Academy of Sciences of the United States of America, 99(6), 3848-3853.

McKeller, R. N., Fowler, J. L., Cunningham, J. J., Warner, N., Smeyne, R. J., Zindy, F., et al.

2001

The proliferative and apoptotic activities of E2F1 in the mouse retina. Oncogene, 20(48), 7073-7084.

Lin, S. -. J., Skapek, S. X., Papermaster, D. S., Hankin, M., & Lee, E. Y. -. P.

2000

Cytogenetics and the biologic basis of sarcomas. Current Opinion in Oncology, 12(4), 315-322.

Skapek, S. X., & Chui, C. H.

2000

Cloning and characterization of a novel kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB. Journal of Biological Chemistry, 275(10), 7212-7223.

Skapek, S. X., Jansen, D., Wei, T. -., McDermott, T., Huang, W., Olson, E. N., et al.

1999

Evidence for apoptosis in dystrophin deficient muscular dystrophy. Journal of Investigative Medicine, 47(2)

Organ, R. J., Bottomley, S., & Skapek, S. X.

1998

Combination chemotherapy using vinblastine and methotrexate for the treatment of progressive desmoid tumor in children. Journal of Clinical Oncology, 16(9), 3021-3027.

Skapek, S. X., Hawk, B. J., Hoffer, F. A., Dahl, G. V., Granowetter, L., Gebhardt, M. C., et al.

1998

Cytogenetics and the biological basis of sarcomas. Current Opinion in Oncology, 10(4), 318-325.

Skapek, S. X., Shaffer, L. G., & Barker, J. A.

1997

The retinoblastoma protein: More than meets the eyes. Progress in Retinal and Eye Research, 16(4), 591-626.

Skapek, S. X., Qian, Y. -., & Lee, E. Y. -. P.

1997

Asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia. Blood, 89(6), 1886-1895.

Parsons, S. K., Skapek, S. X., Neufeld, E. J., Kuhlman, C., Young, M. L., Donnelly, M., et al.

1996

Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRB hyperphosphorylation. Molecular and Cellular Biology, 16(12), 7043-7053.

Skapek, S. X., Rhee, J., Kim, P. S., Novitch, B. G., & Lassar, A. B.

1996

Genes in the RB pathway and their knockout in mice. Seminars in Cancer Biology, 7(5), 279-289.

Lin, S. -. J., Skapek, S. X., & Lee, E. Y. -. P.

1995

Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science, 267(5200), 1022-1024.

Skapek, S. X., Rhee, J., Spicer, D. B., & Lassar, A. B.

1995

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science, 267(5200), 1018-1021.

Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., et al.

1994

Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Current Opinion in Cell Biology, 6(6), 788-794.

Lassar, A. B., Skapek, S. X., & Novitch, B.

1992

Sinusitis and bacteremia caused by flavobacterium meningosepticum in a sixteen-year-old with shwachman diamond syndrome. Pediatric Infectious Disease Journal, 11(5), 411-413.

Skapek, S. X., Jones, W. S., Hoffman, K. M., & Kuskie, M. R.

1991

Melphalan-induced toxicity in nude mice following pretreatment with buthionine sulfoximine. Cancer Chemotherapy and Pharmacology, 28(1), 15-21.

Skapek, S. X., VanDellen, A. F., McMahon, D. P., Postels, D. G., Griffith, O. W., Bigner, D. D., et al.

1989

Dexamethasone therapy for bacterial meningitis. New England Journal of Medicine, 320(7), 463-465.

Skapek, S. X., Ottolini, M. G., Havens, P. L., Kelly, K. J., Hoffman, G. M., Day, S. E., et al.

1989

Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts. Journal of Neuropathology and Experimental Neurology, 48(1), 48-68.

He, X., Skapek, S. X., Wikstrand, C. J., Friedman, H. S., Trojanowski, J. Q., Kemshead, J. T., et al.

1988

Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice. Cancer Research, 48(10), 2764-2767.

Skapek, S. X., Colvin, O. M., Griffith, O. W., Elion, G. B., Bigner, D. D., & Friedman, H. S.

1988

Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents. Cancer Research, 48(15), 4189-4195.

Friedman, H. S., Colvin, O. M., Skapek, S. X., Ludeman, S. M., Elion, G. B., Schold Jr., S. C., et al.

1988

Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma. Cancer Research, 48 (19), 5397-5402.

Friedman, H. S., Skapek, S. X., Colvin, O. M., Elion, G. B., Blum, M. R., Savina, P. M., et al.

1988

Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts. Biochemical Pharmacology, 37(22), 4313-4317.

Skapek, S. X., Colvin, O. M., Griffith, O. W., Groothuis, D. R., Colapinto, E. V., Lee, Y., et al.